In May, the US Food and Drug Incumbency had received more than 40 reports of NAION involving powerlessness drugs but had not determined whether the treatments were responsible.
A spokesperson from Pfizer told Reuters that a drill of 103 sildenafil clinical trials involving more than 13,000 patients found no reports of NAION. But the complement has changed the mark on sildenafil to note reports of NAION. Eli Lilly has also changed its labels on tadalafil 20mg.
Dr. Pomeranz said that the intellect NAION had not shown up in the pre-marketing clinical trials of these drugs may simply relate to a "numbers game."
"If there are millions of prescriptions out there for these drugs and, let's say, 60 cases of NAION, then it is unlikely that a learning of a few thousand patients is going away. This is true with a lot of drugs: it isn't until a lot of prescriptions have been written that some rare side effects aerofoil."
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