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Sunday, November 25, 2007

Rimonabant May Reduce Risk for Diabetes Complications.

The RIO-Diabetes learning, which was performed in 159 centers in 11 countries, showed that rimonabant 20 mg once daily can reduce body free weight and improve cardiovascular and metabolic risk factors in obese patients with type 2 diabetes.
Rimonabant, a selective cannabinoid type 1 structure medicine, significantly improved cardiometabolic risk factors, including importance, HbA1C levels, fasting glucose levels, high-density-lipoprotein (HDL) cholesterol levels, triglyceride levels, systolic genealogy urgency, and area mete in obese type 2 diabetic patients whose information was uncontrolled with metformin or sulfonylureas. Subjects in this double-blinded contest were randomized to receive rimonabant 20 mg/day, rimonabant 5 mg/day, or medicament for 1 year. All patients were also treated with an oral hypoglycemic drug, as prescribed by their physician.
At the end of 1 year, patients receiving rimonabant 20 mg had an scale value artifact loss of 5.3 kg, compared with 1.4 kg in the medicine chemical group. Scale value levels of HbA1C decreased by 0.7 percent in the rimonabant 20-mg building block from a line property of 7.3%, but increased in the medicine set by 0.1%. In fact, 43% of all subjects treated with rimonabant 20 mg/day achieved an HbA1C property of less than 6.5%, compared with just 21% in the vesper unit. The effects of the rimonabant 5 mg/day were not as significant.

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